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Tdark
PNLIPRP3
Pancreatic lipase-related protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369230
  • ENSP00000358232
  • ENSG00000203837
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
metabolite
0.88
cell type or tissue
0.58
microRNA
0.48
gene perturbation
0.47


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.71   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 107   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.71   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
influenza A (H1N1)
2
1
0
8.5
45.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
influenza A (H1N1)
0
8.5
45.5
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
pancreatic lipase related protein 3
VGNC:7856
739593
Horse
pancreatic lipase related protein 3
VGNC:21624
100067785
Cow
pancreatic lipase related protein 3
VGNC:33083
531271
Pig
pancreatic lipase related protein 3
100521689
Platypus
pancreatic lipase-related protein 3-like
100092999
Species
Name
OMA
EggNOG
Inparanoid
Chimp
pancreatic lipase related protein 3
Horse
pancreatic lipase related protein 3
Cow
pancreatic lipase related protein 3
Pig
pancreatic lipase related protein 3
Platypus
pancreatic lipase-related protein 3-like
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q17RR3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (6)
Digestion (R-HSA-8935690)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Digestion
Reactome
Digestion and absorption
Reactome
Digestion of dietary lipid
Name
Explore in Pharos
Explore in Source
Digestion
Digestion and absorption
Digestion of dietary lipid
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-EC
Protein-Protein Interactions (61)
1 – 10 of 61
LIPE
Tchem
Family: Enzyme
Novelty: 0.00169872
Score: 0.949
Data Source: STRINGDB
LPL
Tchem
Family: Enzyme
Novelty: 0.00057058
Score: 0.915
Data Source: STRINGDB
MGLL
Tchem
Family: Enzyme
Novelty: 0.00196912
Score: 0.909
Data Source: STRINGDB
AGK
Tbio
Family: Enzyme
Novelty: 0.00919083
Score: 0.9
Data Source: STRINGDB
PNPLA2
Tchem
Family: Enzyme
Novelty: 0.00149181
Score: 0.886
Data Source: STRINGDB
CEL
Tchem
Family: Enzyme
Novelty: 0.00156761
Score: 0.883
Data Source: STRINGDB
LIPF
Tclin
Family: Enzyme
Novelty: 0.03073254
Score: 0.868
Data Source: STRINGDB
PNPLA3
Tbio
Family: Enzyme
Novelty: 0.00180327
Score: 0.841
Data Source: STRINGDB
LIPC
Tchem
Family: Enzyme
Novelty: 0.00219107
Score: 0.819
Data Source: STRINGDB
LIPG
Tchem
Family: Enzyme
Novelty: 0.00412129
Score: 0.809
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.71

PubMed score by year
PubTator Score  0.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer