You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
EXOC3L4
Exocyst complex component 3-like protein 4

Protein Classes
Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380069
  • ENSP00000369409
  • ENSG00000205436

Symbol
  • C14orf73
  • C14orf73
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
phenotype
0.66
cell type or tissue
0.52
tissue sample
0.52
PubMedID
0.51
tissue
0.47


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.73   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 11   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.73   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 11   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
3
2
2
6.3
96.2
mean platelet volume
2
4
4
94.7
platelet count
3
4
3
3.5
92.9
1
1
0
1.4
75.4
platelet crit
2
2
2
34.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
2
6.3
96.2
mean platelet volume
4
94.7
platelet count
3
3.5
92.9
0
1.4
75.4
platelet crit
2
34.4
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
exocyst complex component 3 like 4
VGNC:8515
467564
Macaque
exocyst complex component 3 like 4
696187
Mouse
MGI:1921363
74190
Rat
RGD:1307749
299338
Horse
exocyst complex component 3 like 4
VGNC:17722
100058968
Species
Name
OMA
EggNOG
Inparanoid
Chimp
exocyst complex component 3 like 4
Macaque
exocyst complex component 3 like 4
Mouse
Rat
Horse
exocyst complex component 3 like 4
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q17RC7-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (62)
1 – 10 of 62
EXOC7
Tbio
Novelty: 0.00852508
Score: 0.872
Data Source: STRINGDB
EXOC2
Tbio
Novelty: 0.01434464
Score: 0.822
Data Source: STRINGDB
EXOC8
Tbio
Novelty: 0.03090842
Score: 0.816
Data Source: STRINGDB
EXOC5
Tbio
Novelty: 0.02200205
Score: 0.81
Data Source: STRINGDB
EXOC4
Tbio
Novelty: 0.01636648
Score: 0.808
Data Source: STRINGDB
EXOC1
Tbio
Novelty: 0.01073858
Score: 0.716
Data Source: STRINGDB
ALS2CL
Tbio
Novelty: 0.28104121
Score: 0.711
Data Source: STRINGDB
EXOC6B
Tbio
Novelty: 0.11301293
Score: 0.691
Data Source: STRINGDB
EXOC6
Tbio
Novelty: 0.01886811
Score: 0.691
Data Source: STRINGDB
KIAA2012
Tdark
Novelty: 21
Score: 0.645
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.73

PubMed score by year
PubTator Score  1.67

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer