Tdark LONRF1 LON peptidase N-terminal domain and RING finger protein 1

Protein Summary

Uniprot Accession IDs

• Q17RB8
• B4DM29
• B4DU84
• Q8TEA0
• Q9BSV1

Gene Name

• LONRF1

Ensembl ID

• ENST00000398246
• ENSP00000381298
• ENSG00000154359

Symbol

• RNF191
• RNF191

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.99
cellular component	0.83
transcription factor perturbation	0.8
kinase perturbation	0.76
histone modification site profile	0.7

Protein Classes

PANTHER Classes

Protein / ... / Ubiquitin-protein Ligase / Lon Peptidase N-terminal Domain And Ring Finger Protein 1

DTO Classes

Protein / Enzyme / Ligase / Ubiquitin-protein Ligase / Lon Peptidase N-terminal Domain And Ring Finger Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.1   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 107   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.1   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0