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Tdark
TATDN3
Putative deoxyribonuclease TATDN3

Protein Summary
Description
Putative deoxyribonuclease.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366973
  • ENSP00000355940
  • ENSG00000203705
  • ENST00000366974
  • ENSP00000355941
  • ENST00000526641
  • ENSP00000434801
  • ENST00000531963
  • ENSP00000433755
  • ENST00000532324
  • ENSP00000431376
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.89
transcription factor binding site profile
0.61
tissue sample
0.57
virus perturbation
0.55
transcription factor
0.54


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 28   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 28   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
2
2
81.4
hematocrit
2
2
2
74
reticulocyte count
1
1
1
44.2
childhood onset asthma
1
1
0
1.1
40.7
reticulocyte measurement
1
1
1
29
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
81.4
hematocrit
2
74
reticulocyte count
1
44.2
childhood onset asthma
0
1.1
40.7
reticulocyte measurement
1
29
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
TatD DNase domain containing 3
VGNC:1662
457723
Macaque
TatD DNase domain containing 3
715769
Mouse
MGI:1916222
68972
Dog
TatD DNase domain containing 3
VGNC:47124
490284
Horse
TatD DNase domain containing 3
VGNC:23889
100053661
Species
Name
OMA
EggNOG
Inparanoid
Chimp
TatD DNase domain containing 3
Macaque
TatD DNase domain containing 3
Mouse
Dog
TatD DNase domain containing 3
Horse
TatD DNase domain containing 3
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q17R31-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (19)
1 – 10 of 19
EIF1AD
Tdark
Novelty:  0.23915521
Score:  0.771
Data Source:  STRINGDB
USP49
Tbio
Family:  Enzyme
Novelty:  0.15047537
Score:  0.717
Data Source:  STRINGDB
SEC61A2
Tdark
Novelty:  1.46395791
Score:  0.655
Data Source:  STRINGDB
ISYNA1
Tbio
Family:  Enzyme
Novelty:  0.00302974
Score:  0.638
Data Source:  STRINGDB
QTRT2
Tbio
Family:  Enzyme
Novelty:  0.17017926
Score:  0.593
Data Source:  STRINGDB
CSAD
Tbio
Family:  Enzyme
Novelty:  0.01293688
Score:  0.589
Data Source:  STRINGDB
TRAIP
Tbio
Family:  Enzyme
Novelty:  0.04163226
Score:  0.573
Data Source:  STRINGDB
SEC61A1
Tbio
Novelty:  0.0026034
Score:  0.535
Data Source:  STRINGDB
MFSD14B
Tdark
Novelty:  0.62886297
Score:  0.499
Data Source:  STRINGDB
MRPL39
Tbio
Novelty:  0.14346457
Score:  0.458
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.11

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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