PCK2
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.98 | ||
molecular function | 0.93 | ||
transcription factor perturbation | 0.88 | ||
biological process | 0.8 | ||
small molecule perturbation | 0.77 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gluconeogenesis | ||||
Reactome | Glucose metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of carbohydrates | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gluconeogenesis | ||||
Glucose metabolism | ||||
Metabolism | ||||
Metabolism of carbohydrates | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 1 | 1 | 1 | 55.2 | ||||||
self reported educational attainment | 1 | 1 | 1 | 55.2 | ||||||
liver disease biomarker | 1 | 1 | 1 | 48.5 | ||||||
liver fat measurement | 1 | 1 | 1 | 48.5 | ||||||
liver disease biomarker | 1 | 1 | 1 | 48.5 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
self reported educational attainment | 1 | 55.2 | |||||
self reported educational attainment | 1 | 55.2 | |||||
liver disease biomarker | 1 | 48.5 | |||||
liver fat measurement | 1 | 48.5 | |||||
liver disease biomarker | 1 | 48.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | phosphoenolpyruvate carboxykinase 2, mitochondrial | VGNC:8219 | 452807 | |||||
Macaque | phosphoenolpyruvate carboxykinase 2, mitochondrial | 714922 | ||||||
Mouse | MGI:1860456 | 74551 | ||||||
Dog | phosphoenolpyruvate carboxykinase 2, mitochondrial | VGNC:44308 | 480255 | |||||
Horse | phosphoenolpyruvate carboxykinase 2, mitochondrial | VGNC:21204 | 100054903 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | phosphoenolpyruvate carboxykinase 2, mitochondrial | |||||
Macaque | phosphoenolpyruvate carboxykinase 2, mitochondrial | |||||
Mouse | ||||||
Dog | phosphoenolpyruvate carboxykinase 2, mitochondrial | |||||
Horse | phosphoenolpyruvate carboxykinase 2, mitochondrial | |||||
PMID | Year | Title |
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