DECR1
2,4-dienoyl-CoA reductase, mitochondrial
Protein Summary
Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]
- ENST00000220764
- ENSP00000220764
- ENSG00000104325
- ENST00000522161
- ENSP00000429779
- DECR
- SDR18C1
- DECR
- NADPH
- SDR18C1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.97 | ||
disease perturbation | 0.95 | ||
interacting protein | 0.93 | ||
transcription factor perturbation | 0.88 | ||
cellular component | 0.77 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 74.81 (req: < 5)
Gene RIFs: 15 (req: <= 3)
Antibodies: 210 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 74.81 (req: >= 5)
Gene RIFs: 15 (req: > 3)
Antibodies: 210 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0