IFI16
Gamma-interferon-inducible protein 16
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 1 | ||
virus perturbation | 1 | ||
biological process | 0.99 | ||
kinase perturbation | 0.99 | ||
disease perturbation | 0.97 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytosolic sensors of pathogen-associated DNA | ||||
Reactome | IRF3-mediated induction of type I IFN | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | STING mediated induction of host immune responses | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytosolic sensors of pathogen-associated DNA | ||||
IRF3-mediated induction of type I IFN | ||||
Immune System | ||||
Innate Immune System | ||||
STING mediated induction of host immune responses | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
leukocyte count | 3 | 2 | 5 | 95.6 | |||||
granulocyte count | 1 | 1 | 1 | 84 | |||||
erythrocyte count | 1 | 1 | 1 | 83.6 | |||||
hemoglobin measurement | 1 | 1 | 1 | 83.6 | |||||
hematocrit | 1 | 1 | 1 | 83.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
leukocyte count | 5 | 95.6 | |||||
granulocyte count | 1 | 84 | |||||
erythrocyte count | 1 | 83.6 | |||||
hemoglobin measurement | 1 | 83.6 | |||||
hematocrit | 1 | 83.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | interferon gamma inducible protein 16 | VGNC:8913 | 457424 | |||||
Macaque | interferon gamma inducible protein 16 | 719253 | ||||||
Mouse | MGI:101847 | 226695 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | interferon gamma inducible protein 16 | |||||
Macaque | interferon gamma inducible protein 16 | |||||
Mouse | ||||||
PMID | Year | Title |
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