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Tbio
MLANA
Melanoma antigen recognized by T-cells 1

Protein Summary
Description
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000381471
  • ENSP00000370880
  • ENSG00000120215
  • ENST00000381476
  • ENSP00000370885
  • ENST00000381477
  • ENSP00000370886

Symbol
  • MART1
  • MART1
  • MART-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.77
cell line
0.72
cellular component
0.68
biological term
0.67
PubMedID
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1757.18   (req: < 5)
Gene RIFs: 53   (req: <= 3)
Antibodies: 2080   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1757.18   (req: >= 5)
Gene RIFs: 53   (req: > 3)
Antibodies: 2080   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0