AANAT
Serotonin N-acetyltransferase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
co-expressed gene | 0.87 | ||
biological process | 0.73 | ||
cell type or tissue | 0.61 | ||
disease perturbation | 0.56 | ||
transcription factor | 0.55 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of amine-derived hormones | ||||
Reactome | Metabolism of amino acids and derivatives | ||||
Reactome | Serotonin and melatonin biosynthesis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of amine-derived hormones | ||||
Metabolism of amino acids and derivatives | ||||
Serotonin and melatonin biosynthesis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 8 | 10 | 98.1 | |||||
reticulocyte count | 7 | 6 | 16 | 97.3 | |||||
lymphocyte count | 3 | 4 | 5 | 95.6 | |||||
mean reticulocyte volume | 1 | 2 | 2 | 79.2 | |||||
leukocyte count | 1 | 2 | 2 | 76.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte measurement | 10 | 98.1 | |||||
reticulocyte count | 16 | 97.3 | |||||
lymphocyte count | 5 | 95.6 | |||||
mean reticulocyte volume | 2 | 79.2 | |||||
leukocyte count | 2 | 76.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | aralkylamine N-acetyltransferase | VGNC:6317 | 503504 | |||||
Macaque | aralkylamine N-acetyltransferase | 706924 | ||||||
Mouse | MGI:1328365 | 11298 | ||||||
Rat | RGD:2006 | 25120 | ||||||
Dog | aralkylamine N-acetyltransferase | VGNC:37413 | 483331 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | aralkylamine N-acetyltransferase | |||||
Macaque | aralkylamine N-acetyltransferase | |||||
Mouse | ||||||
Rat | ||||||
Dog | aralkylamine N-acetyltransferase | |||||
PMID | Year | Title |
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