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Tbio
ZNF74
Zinc finger protein 74

Protein Classes
Protein Summary
Description
May play a role in RNA metabolism.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000400451
  • ENSP00000383301
  • ENSG00000185252
  • ENST00000403682
  • ENSP00000384750
  • ENST00000405993
  • ENSP00000385855
  • ENST00000611540
  • ENSP00000483077

Symbol
  • ZNF520
  • COS52
  • hZNF7
  • ZFP520
  • ZNF520
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.7
histone modification site profile
0.69
protein domain
0.58
small molecule perturbation
0.58
cellular component
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.83   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.83   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (8)
Gene expression (Transcription) (R-HSA-74160)

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Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (45)
1 – 10 of 45
TNNC2
Tbio
Novelty: 0.11856592
p_int: 0.999999826
p_ni: 1.68e-7
p_wrong: 6e-9
Data Source: BioPlex
LZTS2
Tbio
Novelty: 0.12012012
p_int: 0.999994669
p_ni: 0.000005325
p_wrong: 6e-9
Data Source: BioPlex
VWCE
Tbio
Novelty: 0.10129635
p_int: 0.999986352
p_ni: 5.7e-8
p_wrong: 0.000013592
Score: 0.251
Data Source: BioPlex,STRINGDB
DVL1
Tchem
Novelty: 0.00460899
p_int: 0.999417199
p_ni: 3.6e-8
p_wrong: 0.000582765
Data Source: BioPlex
KIF7
Tbio
Novelty: 0.03202305
p_int: 0.999021435
p_ni: 0.000978563
p_wrong: 1e-9
Data Source: BioPlex
P3H2
Tbio
Family: Enzyme
Novelty: 0.00315791
p_int: 0.998874713
p_ni: 0.000408874
p_wrong: 0.000716414
Data Source: BioPlex
RBAK
Tbio
Family: TF
Novelty: 0.15225666
p_int: 0.997692466
p_ni: 0.00170427
p_wrong: 0.000603264
Data Source: BioPlex
FBXO11
Tbio
Novelty: 0.03932673
p_int: 0.995927583
p_ni: 0.004072417
Data Source: BioPlex
SNX18
Tbio
Novelty: 0.16877637
p_int: 0.995709324
p_ni: 0.004263827
p_wrong: 0.000026849
Data Source: BioPlex
TCEAL5
Tdark
Novelty: 6
p_int: 0.995493456
p_ni: 0.000157776
p_wrong: 0.004348768
Data Source: BioPlex
Publication Statistics
PubMed Score  7.83

PubMed score by year
PubTator Score  9.39

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer