SNRNP35
U11/U12 small nuclear ribonucleoprotein 35 kDa protein
Protein Summary
The protein encoded by this gene is a homolog of the U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, which is a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. Alternative splicing results in multiple transcript variants encoding two distinct isoforms and representing a non-protein coding variant. [provided by RefSeq, Aug 2013]
- ENST00000350887
- ENSP00000340774
- ENSG00000184209
- ENST00000412157
- ENSP00000403310
- ENST00000526639
- ENSP00000432595
- HM1
- U1SNRNPBP
- HM-1
- U1SNRNPBP
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor binding site profile | 0.81 | ||
cell type or tissue | 0.73 | ||
tissue sample | 0.65 | ||
transcription factor | 0.63 | ||
cell line | 0.62 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.19 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 46 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.19 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 46 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0