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Tbio
LY6E
Lymphocyte antigen 6E

Protein Summary
Description
Involved in T-cell development. Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000292494
  • ENSP00000292494
  • ENSG00000160932
  • ENST00000429120
  • ENSP00000414307
  • ENST00000520466
  • ENSP00000428572
  • ENST00000521003
  • ENSP00000428169
  • ENST00000521699
  • ENSP00000427915
  • ENST00000522024
  • ENSP00000428442
  • ENST00000522971
  • ENSP00000428159
  • ENST00000619718
  • ENSP00000482517
  • ENSG00000278032
  • ENST00000631568
  • ENSP00000488891
  • ENST00000632424
  • ENSP00000488421
  • ENST00000632516
  • ENSP00000487664
  • ENST00000632519
  • ENSP00000488443
  • ENST00000632812
  • ENSP00000488556
  • ENST00000633451
  • ENSP00000488559

Symbol
  • 9804
  • RIGE
  • SCA2
  • TSA1
  • RIGE
  • SCA2
  • RIG-E
  • SCA-2
  • TSA-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.96
PubMedID
0.92
transcription factor perturbation
0.91
gene perturbation
0.84
kinase perturbation
0.81


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 167.26   (req: < 5)
Gene RIFs: 17   (req: <= 3)
Antibodies: 186   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 167.26   (req: >= 5)
Gene RIFs: 17   (req: > 3)
Antibodies: 186   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0