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Tbio
ZNF77
Zinc finger protein 77

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000314531
  • ENSP00000319053
  • ENSG00000175691

Symbol
  • pT1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease
0.85
cell type or tissue
0.81
histone modification site profile
0.73
protein domain
0.58
tissue sample
0.57


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 785.53   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 60   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 785.53   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (21)
1 – 10 of 21
VWCE
Tbio
Novelty:  0.09328341
p_int:  0.999990234
p_ni:  1.94e-7
p_wrong:  0.000009572
Score:  0.166
Data Source:  BioPlex,STRINGDB
FBLN2
Tbio
Novelty:  0.01340024
p_int:  0.99987679
p_ni:  0.000010046
p_wrong:  0.000113165
Data Source:  BioPlex
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.958184998
p_ni:  6.51e-7
p_wrong:  0.041814351
Score:  0.918
Data Source:  BioPlex,STRINGDB
NICN1
Tdark
Novelty:  0.32909597
Score:  0.81
Data Source:  STRINGDB
P2RX3
Tchem
Family:  IC
Novelty:  0.00203167
Score:  0.806
Data Source:  STRINGDB
F2
Tclin
Family:  Enzyme
Novelty:  0.00004833
Score:  0.723
Data Source:  STRINGDB
P2RX2
Tchem
Family:  IC
Novelty:  0.00241146
Score:  0.71
Data Source:  STRINGDB
PTS
Tbio
Family:  Enzyme
Novelty:  0.00279396
Score:  0.655
Data Source:  STRINGDB
RGS7BP
Tbio
Novelty:  0.05820527
Score:  0.611
Data Source:  STRINGDB
PRDX3
Tbio
Family:  Enzyme
Novelty:  0.00340119
Score:  0.554
Data Source:  STRINGDB
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
25
78.6
1
1
0
50
76.5
Ischemic stroke
1
1
0
12.5
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
25
78.6
0
50
76.5
Ischemic stroke
0
12.5
24.5
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 77
VGNC:2126
455578
Macaque
zinc finger protein 77
712142
Dog
zinc finger protein 77
100686484
Horse
zinc finger protein 77
100060110
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 77
Macaque
zinc finger protein 77
Dog
zinc finger protein 77
Horse
zinc finger protein 77
Publication Statistics
PubMed Score 785.53
PubMed score by year
PubTator Score 1709.91
PubTator score by year