You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ZKSCAN8
Zinc finger protein with KRAB and SCAN domains 8

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000330236
  • ENSP00000332750
  • ENSG00000198315
  • ENST00000457389
  • ENSP00000402948
  • ENST00000536028
  • ENSP00000439117
  • ENST00000606198
  • ENSP00000475589

Symbol
  • ZNF192
  • LD5-1
  • ZNF192
  • ZSCAN40
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
microRNA
0.73
cell type or tissue
0.72
transcription factor binding site profile
0.68
histone modification site profile
0.58


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.68   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 173   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.68   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 173   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (28)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
6
0
1.1
92.3
1
4
0
1.1
83.1
depressive symptom measurement
1
2
2
75.7
wellbeing measurement
3
2
3
75
low density lipoprotein cholesterol measurement
1
1
1
73.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
92.3
0
1.1
83.1
depressive symptom measurement
2
75.7
wellbeing measurement
3
75
low density lipoprotein cholesterol measurement
1
73.6
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger with KRAB and SCAN domains 8
VGNC:7944
471912
Mouse
MGI:1913815
93681
Dog
zinc finger with KRAB and SCAN domains 8
VGNC:49668
100687919
Horse
zinc finger with KRAB and SCAN domains 8
VGNC:25241
100061924
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger with KRAB and SCAN domains 8
Mouse
Dog
zinc finger with KRAB and SCAN domains 8
Horse
zinc finger with KRAB and SCAN domains 8
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q15776-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (96)
1 – 10 of 96
ZKSCAN3
Tbio
Family:  TF
Novelty:  0.06833314
p_int:  0.999999192
p_ni:  8.08e-7
Data Source:  BioPlex
CUL9
Tbio
Novelty:  0.1104365
p_int:  0.999987273
p_ni:  0.000012727
Data Source:  BioPlex
CHD3
Tbio
Family:  Epigenetic
Novelty:  0.00657278
p_int:  0.999986549
p_ni:  0.000013451
Data Source:  BioPlex
RGS3
Tbio
Novelty:  0.01749541
p_int:  0.999971351
p_ni:  0.000028646
p_wrong:  4e-9
Score:  0.222
Data Source:  BioPlex,STRINGDB
SCAND1
Tbio
Novelty:  0.06863895
p_int:  0.999968556
p_ni:  0.000031378
p_wrong:  6.6e-8
Data Source:  BioPlex
ZNF174
Tbio
Family:  TF
Novelty:  0.05970272
p_int:  0.999943573
p_ni:  0.000055466
p_wrong:  9.61e-7
Score:  0.326
Data Source:  BioPlex,STRINGDB
ZNF708
Tdark
Family:  TF
Novelty:  0.45365748
p_int:  0.999879908
p_ni:  0.000063704
p_wrong:  0.000056388
Data Source:  BioPlex
ZKSCAN1
Tbio
Family:  TF
Novelty:  0.08190662
p_int:  0.999836875
p_ni:  0.000163124
p_wrong:  1e-9
Data Source:  BioPlex
ZSCAN20
Tdark
Family:  TF
Novelty:  0.37441538
p_int:  0.999740998
p_ni:  0.000258127
p_wrong:  8.76e-7
Score:  0.653
Data Source:  BioPlex,STRINGDB
CUL7
Tbio
Novelty:  0.02183958
p_int:  0.999694436
p_ni:  0.000305565
Data Source:  BioPlex
Publication Statistics
PubMed Score  5.68

PubMed score by year
PubTator Score  2.42

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: