SPEG
Striated muscle preferentially expressed protein kinase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
molecular function | 0.91 | ||
PubMedID | 0.8 | ||
small molecule perturbation | 0.79 | ||
transcription factor | 0.72 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 3 | 3 | 4 | 88.8 | |||||
creatinine measurement | 1 | 2 | 2 | 85.6 | |||||
electrocardiography | 1 | 1 | 82 | 75.9 | |||||
soluble triggering receptor expressed on myeloid cells 2 measurement | 1 | 1 | 0 | 15744.7 | 53.3 | ||||
vital capacity | 1 | 1 | 1 | 40.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 4 | 88.8 | |||||
creatinine measurement | 2 | 85.6 | |||||
electrocardiography | 82 | 75.9 | |||||
soluble triggering receptor expressed on myeloid cells 2 measurement | 0 | 15744.7 | 53.3 | ||||
vital capacity | 1 | 40.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | SPEG complex locus | 743624 | ||||||
Macaque | SPEG complex locus | 703645 | ||||||
Mouse | MGI:109282 | 11790 | ||||||
Rat | RGD:2124 | 363256 | ||||||
Dog | SPEG complex locus | VGNC:49703 | 478924 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | SPEG complex locus | |||||
Macaque | SPEG complex locus | |||||
Mouse | ||||||
Rat | ||||||
Dog | SPEG complex locus | |||||
PMID | Year | Title |
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