Tbio ZNF174 Zinc finger protein 174

Protein Summary

Description

Transcriptional repressor. This gene encodes a protein with three Cys2-His2-type zinc fingers in the carboxy-terminus, a putative nuclear localization signal, and an amino-terminus SCAN box which forms homodimers. This protein is believed to function as a transcriptional repressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Uniprot Accession IDs

• Q15697
• Q53Y68
• Q9BQ34

Gene Name

• ZNF174

Ensembl ID

• ENST00000268655
• ENSP00000268655
• ENSG00000103343
• ENST00000344823
• ENSP00000339781
• ENST00000571936
• ENSP00000460397
• ENST00000575752
• ENSP00000461502

Symbol

• ZSCAN8
• ZSCAN8

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
histone modification site profile	0.87
molecular function	0.67
transcription factor binding site profile	0.67
tissue sample	0.65

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 141.73   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 201   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 141.73   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 201   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0