Tbio PPP1R7 Protein phosphatase 1 regulatory subunit 7

Protein Summary

Description

Regulatory subunit of protein phosphatase 1. This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Accession IDs

• Q15435
• B4DFD4
• B5MCY6
• Q9UQE5
• Q9UQE6
• Q9Y6K4

Gene Name

• PPP1R7

Ensembl ID

• ENST00000234038
• ENSP00000234038
• ENSG00000115685
• ENST00000272983
• ENSP00000272983
• ENST00000401987
• ENSP00000385466
• ENST00000402734
• ENSP00000385012
• ENST00000406106
• ENSP00000385022
• ENST00000407025
• ENSP00000385657

Symbol

• SDS22
• SDS22

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
co-expressed gene	0.98
disease perturbation	0.96
transcription factor perturbation	0.91
histone modification site profile	0.87
transcription factor binding site profile	0.84

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 55.79   (req: < 5)

Gene RIFs: 11   (req: <= 3)

Antibodies: 227   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 55.79   (req: >= 5)

Gene RIFs: 11   (req: > 3)

Antibodies: 227   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0