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Tbio
TOMM20
Mitochondrial import receptor subunit TOM20 homolog

Protein Summary
Description
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366607
  • ENSP00000355566
  • ENSG00000173726

Symbol
  • KIAA0016
  • MAS20
  • MOM19
  • TOM20
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.99
transcription factor perturbation
0.94
virus perturbation
0.94
transcription factor binding site profile
0.93
disease perturbation
0.87


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 342.76   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 192   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 342.76   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 192   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (180)
TOMM22
Tbio
Novelty:  0.01217913
Score:  0.998
Data Source:  STRINGDB
TOMM70
Tbio
Novelty:  0.00943973
Score:  0.996
Data Source:  STRINGDB
VDAC1
Tbio
Novelty:  0.0011441
Score:  0.994
Data Source:  STRINGDB
TOMM40
Tbio
Novelty:  0.0041507
Score:  0.993
Data Source:  STRINGDB
PINK1
Tbio
Family:  Kinase
Novelty:  0.00100973
Score:  0.991
Data Source:  STRINGDB
TOMM7
Tbio
Novelty:  0.03885154
Score:  0.99
Data Source:  STRINGDB
TOMM5
Tdark
Novelty:  0.07962801
Score:  0.975
Data Source:  STRINGDB
VDAC2
Tchem
Novelty:  0.00575936
Score:  0.973
Data Source:  STRINGDB
TOMM6
Tbio
Novelty:  0.1033676
Score:  0.971
Data Source:  STRINGDB
HSPA9
Tchem
Novelty:  0.00235171
Score:  0.971
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (11)
Autophagy (R-HSA-9612973)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 11
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Autophagy
Reactome
Cellular responses to external stimuli
Reactome
Deubiquitination
Reactome
Macroautophagy
Reactome
Metabolism of proteins
Name
Explore in Pharos
Explore in Source
Autophagy
Cellular responses to external stimuli
Deubiquitination
Macroautophagy
Metabolism of proteins
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
translocase of outer mitochondrial membrane 20
VGNC:8554
457833
Mouse
MGI:1915202
67952
Rat
RGD:708467
266601
Dog
translocase of outer mitochondrial membrane 20
VGNC:49025
100682999
Horse
translocase of outer mitochondrial membrane 20
VGNC:49074
100058806
Species
Name
OMA
EggNOG
Inparanoid
Chimp
translocase of outer mitochondrial membrane 20
Mouse
Rat
Dog
translocase of outer mitochondrial membrane 20
Horse
translocase of outer mitochondrial membrane 20
Publication Statistics
PubMed Score 342.76
PubMed score by year
PubTator Score 92.33
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title