PTPRK
Receptor-type tyrosine-protein phosphatase kappa
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
trait | 0.97 | ||
transcription factor perturbation | 0.94 | ||
biological process | 0.82 | ||
disease perturbation | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | EGFR downregulation | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by EGFR | ||||
Reactome | Signaling by Receptor Tyrosine Kinases | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
EGFR downregulation | ||||
Signal Transduction | ||||
Signaling by EGFR | ||||
Signaling by Receptor Tyrosine Kinases | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
5 | 5 | 0 | 1.1 | 87 | ||||||
5 | 5 | 0 | 1.1 | 87 | ||||||
3 | 3 | 0 | 1.2 | 85.6 | ||||||
3 | 3 | 0 | 1.2 | 85.6 | ||||||
childhood onset asthma | 1 | 1 | 0 | 1.1 | 64.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.1 | 87 | |||||
0 | 1.1 | 87 | |||||
0 | 1.2 | 85.6 | |||||
0 | 1.2 | 85.6 | |||||
childhood onset asthma | 0 | 1.1 | 64.4 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | protein tyrosine phosphatase, receptor type K | VGNC:11196 | 745734 | |||||
Mouse | MGI:103310 | 19272 | ||||||
Rat | RGD:619706 | 360302 | ||||||
Dog | protein tyrosine phosphatase, receptor type K | VGNC:45191 | 476290 | |||||
Horse | protein tyrosine phosphatase, receptor type K | VGNC:22034 | 100073063 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | protein tyrosine phosphatase, receptor type K | |||||
Mouse | ||||||
Rat | ||||||
Dog | protein tyrosine phosphatase, receptor type K | |||||
Horse | protein tyrosine phosphatase, receptor type K | |||||
PMID | Year | Title |
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