Tbio RRS1 Ribosome biogenesis regulatory protein homolog

Protein Summary

Description

Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.

Uniprot Accession IDs

• Q15050
• Q9BUX8

Gene Name

• RRS1

Ensembl ID

• ENST00000320270
• ENSP00000322396
• ENSG00000179041

Symbol

• KIAA0112
• RRR

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.96
small molecule perturbation	0.92
interacting protein	0.83
virus perturbation	0.83
PubMedID	0.71

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribosomal Protein / Ribosome Biogenesis Regulatory Protein Homolog

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribosomal Protein / Ribosome Biogenesis Regulatory Protein Homolog

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 158.76   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 183   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 158.76   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 183   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0