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Tdark
RTP5
Receptor-transporting protein 5

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000343216
  • ENSP00000345374
  • ENSG00000188011
  • ENST00000617264
  • ENSP00000482049
  • ENSG00000277949

Symbol
  • C2orf85
  • CXXC11
  • Z3CXXC5
  • CXXC11
  • C2orf85
  • Z3CXXC5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.61
tissue
0.5
cell line
0.47
protein domain
0.41
cellular component
0.33


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 19   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 19   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (385)
1 – 10 of 385
OR14I1
Tdark
Family:  oGPCR
Novelty:  2.51695969
Score:  0.911
Data Source:  STRINGDB
OR2L13
Tdark
Family:  oGPCR
Novelty:  0.3071575
Score:  0.911
Data Source:  STRINGDB
OR13J1
Tdark
Family:  oGPCR
Novelty:  2.15311005
Score:  0.903
Data Source:  STRINGDB
OR56A1
Tdark
Family:  oGPCR
Novelty:  28
Score:  0.9
Data Source:  STRINGDB
OR4X2
Tdark
Family:  oGPCR
Novelty:  2.04538259
Score:  0.9
Data Source:  STRINGDB
OR7G2
Tdark
Family:  oGPCR
Novelty:  2.03014553
Score:  0.9
Data Source:  STRINGDB
OR1B1
Tdark
Family:  oGPCR
Novelty:  0.38284296
Score:  0.9
Data Source:  STRINGDB
OR51I1
Tdark
Family:  oGPCR
Novelty:  5.45454545
Score:  0.9
Data Source:  STRINGDB
OR6K6
Tdark
Family:  oGPCR
Novelty:  1.4520244
Score:  0.9
Data Source:  STRINGDB
OR2G3
Tdark
Family:  oGPCR
Novelty:  2.85932722
Score:  0.9
Data Source:  STRINGDB
Pathways (5)
G alpha (s) signalling events (R-HSA-418555)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
G alpha (s) signalling events
Reactome
GPCR downstream signalling
Reactome
Olfactory Signaling Pathway
Reactome
Signal Transduction
Reactome
Signaling by GPCR
Name
Explore in Pharos
Explore in Source
G alpha (s) signalling events
GPCR downstream signalling
Olfactory Signaling Pathway
Signal Transduction
Signaling by GPCR
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
GWAS Traits (18)
Items per page:
1 – 5 of 18
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cancer antigen 125 measurement
1
4
4
97.2
cancer antigen 125 measurement
1
4
4
97.2
blood protein measurement
1
1
1
86.5
blood protein measurement
1
1
1
86.5
1
1
0
4.2
64
Items per page:
1 – 5 of 18
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cancer antigen 125 measurement
4
97.2
cancer antigen 125 measurement
4
97.2
blood protein measurement
1
86.5
blood protein measurement
1
86.5
0
4.2
64
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Dog
receptor transporter protein 5 (putative)
486214
Cow
receptor transporter protein 5 (putative)
511818
Species
Name
OMA
EggNOG
Inparanoid
Dog
receptor transporter protein 5 (putative)
Cow
receptor transporter protein 5 (putative)
Publication Statistics
PubMed Score 4.00
PubMed score by year
PubTator Score 0.50
PubTator score by year