CLCA4
Calcium-activated chloride channel regulator 4
Protein Summary
May be involved in mediating calcium-activated chloride conductance. The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding. [provided by RefSeq, Dec 2008]
- ENST00000370563
- ENSP00000359594
- ENSG00000016602
- CaCC2
- CaCC
- CaCC2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
molecular function | 0.88 | ||
cell type or tissue | 0.8 | ||
cellular component | 0.73 | ||
protein domain | 0.58 | ||
cell line | 0.57 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 22.22 (req: < 5)
Gene RIFs: 10 (req: <= 3)
Antibodies: 64 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 22.22 (req: >= 5)
Gene RIFs: 10 (req: > 3)
Antibodies: 64 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0