SLC10A1
Sodium/bile acid cotransporter
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.88 | ||
cell type or tissue | 0.84 | ||
drug | 0.75 | ||
disease | 0.67 | ||
kinase perturbation | 0.6 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Bile acid and bile salt metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Metabolism of steroids | ||||
Reactome | Recycling of bile acids and salts | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Bile acid and bile salt metabolism | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Metabolism of steroids | ||||
Recycling of bile acids and salts | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 4 | 2 | 4 | 89.2 | |||||
mean corpuscular hemoglobin concentration | 1 | 1 | 1 | 80.6 | |||||
digit length ratio | 3 | 1 | 4 | 75.4 | |||||
appendicular lean mass | 1 | 2 | 2 | 71.4 | |||||
balding measurement | 1 | 1 | 1 | 64.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
red blood cell distribution width | 4 | 89.2 | |||||
mean corpuscular hemoglobin concentration | 1 | 80.6 | |||||
digit length ratio | 4 | 75.4 | |||||
appendicular lean mass | 2 | 71.4 | |||||
balding measurement | 1 | 64.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 10 member 1 | VGNC:8206 | 453001 | |||||
Macaque | solute carrier family 10 member 1 | 712925 | ||||||
Mouse | MGI:97379 | 20493 | ||||||
Rat | RGD:3681 | 24777 | ||||||
Dog | solute carrier family 10 member 1 | VGNC:46211 | 480372 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | solute carrier family 10 member 1 | |||||
Macaque | solute carrier family 10 member 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 10 member 1 | |||||
PMID | Year | Title |
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