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Tbio
BMS1
Ribosome biogenesis protein BMS1 homolog

Protein Summary
Description
May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus. This gene likely encodes a ribosome assembly protein. A similar protein in yeast functions in 35S-rRNA processing, which includes a series of cleavage steps critical for formation of 40S ribosomes. Related pseudogenes exist on chromosomes 2, 9, 10, 15, 16, and 22.[provided by RefSeq, Mar 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374518
  • ENSP00000363642
  • ENSG00000165733

Symbol
  • BMS1L
  • KIAA0187
  • ACC
  • BMS1L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.92
histone modification site profile
0.91
disease perturbation
0.87
molecular function
0.81
co-expressed gene
0.76


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.05   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.05   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (345)
RCL1
Tbio
Family:  Enzyme
Novelty:  0.02116964
p_int:  0.999941226
p_ni:  0.000058774
Score:  0.999
Data Source:  BioPlex,Reactome,STRINGDB
RPS16
Tbio
Novelty:  0.00261983
p_int:  0.99784786
p_ni:  0.00215214
Score:  0.98
Data Source:  BioPlex,STRINGDB
H1FNT
Tdark
Novelty:  0.05593238
p_int:  0.98676697
p_ni:  0.01323303
Data Source:  BioPlex
RPSA
Tbio
Novelty:  0.00250446
p_int:  0.983576171
p_ni:  0.016423819
p_wrong:  1e-8
Score:  0.922
Data Source:  BioPlex,STRINGDB
DGKZ
Tchem
Family:  Enzyme
Novelty:  0.01312044
p_int:  0.965343345
p_ni:  0.034656655
Data Source:  BioPlex
RPS14
Tbio
Novelty:  0.00576737
p_int:  0.954512996
p_ni:  0.045487004
Score:  0.982
Data Source:  BioPlex,STRINGDB
FGF8
Tbio
Novelty:  0.00155113
p_int:  0.929947733
p_ni:  0.070052267
Data Source:  BioPlex
PDGFB
Tbio
Novelty:  0.00080876
p_int:  0.923826635
p_ni:  0.076173365
Data Source:  BioPlex
H2AFY2
Tbio
Novelty:  0.09948698
p_int:  0.922538839
p_ni:  0.077461161
Data Source:  BioPlex
ZBTB48
Tbio
Family:  TF
Novelty:  0.07020518
p_int:  0.919784168
p_ni:  0.080215832
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
Major pathway of rRNA processing in the nucleolus and cytosol (R-HSA-6791226)

Click on a row in the table to change the structure displayed.

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Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Major pathway of rRNA processing in the nucleolus and cytosol
Reactome
Metabolism of RNA
Reactome
rRNA modification in the nucleus and cytosol
Reactome
rRNA processing
Reactome
rRNA processing in the nucleus and cytosol
Name
Explore in Pharos
Explore in Source
Major pathway of rRNA processing in the nucleolus and cytosol
Metabolism of RNA
rRNA modification in the nucleus and cytosol
rRNA processing
rRNA processing in the nucleus and cytosol
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (11)
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Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
BMS1, ribosome biogenesis factor
VGNC:3816
466051
Macaque
ribosome biogenesis protein BMS1 homolog
718855
Mouse
MGI:2446132
213895
Rat
RGD:1308043
362426
Dog
BMS1, ribosome biogenesis factor
VGNC:38487
477760
Species
Name
OMA
EggNOG
Inparanoid
Chimp
BMS1, ribosome biogenesis factor
Macaque
ribosome biogenesis protein BMS1 homolog
Mouse
Rat
Dog
BMS1, ribosome biogenesis factor
Publication Statistics
PubMed Score 30.05
PubMed score by year
PubTator Score 21.50
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title