IL13RA2
Interleukin-13 receptor subunit alpha-2
Protein Summary
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]
- ENST00000243213
- ENSP00000243213
- ENSG00000123496
- ENST00000371936
- ENSP00000361004
- IL13R
- CT19
- IL-13R
- IL13BP
- CD213A2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
gene perturbation | 1 | ||
tissue | 0.71 | ||
tissue sample | 0.66 | ||
biological term | 0.65 | ||
protein domain | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 35.02 (req: < 5)
Gene RIFs: 84 (req: <= 3)
Antibodies: 507 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 35.02 (req: >= 5)
Gene RIFs: 84 (req: > 3)
Antibodies: 507 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0