Tdark ZNF235 Zinc finger protein 235

Protein Summary

Description

May be involved in transcriptional regulation. This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein is a member of the Kruppel family of zinc finger proteins, and contains Kruppel-associated box (KRAB) A and B domains and 15 tandemly arrayed C2H2-type zinc fingers. It is an ortholog of the mouse Zfp93 protein. This gene is located in a cluster of zinc finger genes on 19q13.2. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q14590
• B4DTQ7
• O14898
• O14899
• Q17RR8

Gene Name

• ZNF235

Ensembl ID

• ENST00000291182
• ENSP00000291182
• ENSG00000159917
• ENST00000650576
• ENSP00000497018

Symbol

• ZFP93
• ZNF270
• HZF6
• ZFP93
• ANF270
• ZNF270

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.89
gene perturbation	0.68
protein domain	0.58
cell line	0.54
transcription factor binding site profile	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.76   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 24   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.76   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0