MCM6
DNA replication licensing factor MCM6
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.99 | ||
co-expressed gene | 0.97 | ||
kinase perturbation | 0.96 | ||
gene perturbation | 0.94 | ||
protein domain | 0.92 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of ATR in response to replication stress | ||||
Reactome | Activation of the pre-replicative complex | ||||
Reactome | Assembly of the pre-replicative complex | ||||
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle Checkpoints | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of ATR in response to replication stress | ||||
Activation of the pre-replicative complex | ||||
Assembly of the pre-replicative complex | ||||
Cell Cycle | ||||
Cell Cycle Checkpoints | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | IntAct | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
leukocyte count | 4 | 4 | 5 | 93.3 | |||||
neutrophil count | 4 | 3 | 4 | 93.1 | |||||
gut microbiome measurement | 5 | 4 | 0 | 7.4 | 90 | ||||
myeloid white cell count | 2 | 2 | 2 | 88.7 | |||||
1,5 anhydroglucitol measurement | 1 | 1 | 0 | 16.9 | 85.7 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
leukocyte count | 5 | 93.3 | |||||
neutrophil count | 4 | 93.1 | |||||
gut microbiome measurement | 0 | 7.4 | 90 | ||||
myeloid white cell count | 2 | 88.7 | |||||
1,5 anhydroglucitol measurement | 0 | 16.9 | 85.7 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | minichromosome maintenance complex component 6 | VGNC:2010 | 741695 | |||||
Macaque | minichromosome maintenance complex component 6 | 707651 | ||||||
Mouse | MGI:1298227 | 17219 | ||||||
Rat | RGD:61967 | 29685 | ||||||
Dog | minichromosome maintenance complex component 6 | VGNC:43086 | 476131 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | minichromosome maintenance complex component 6 | |||||
Macaque | minichromosome maintenance complex component 6 | |||||
Mouse | ||||||
Rat | ||||||
Dog | minichromosome maintenance complex component 6 | |||||
PMID | Year | Title |
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