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Tbio
GBX1
Homeobox protein GBX-1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297537
  • ENSP00000297537
  • ENSG00000164900

Symbol
  • Huh-17
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.63
PubMedID
0.59
biological process
0.58
protein domain
0.58
transcription factor binding site profile
0.57


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.76   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 115   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.76   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
gastrulation brain homeobox 1
VGNC:14095
737612
Mouse
MGI:95667
231044
Rat
RGD:621864
246149
Cow
gastrulation brain homeobox 1
VGNC:53645
518355
Opossum
gastrulation brain homeobox 1
100015412
Species
Name
OMA
EggNOG
Inparanoid
Chimp
gastrulation brain homeobox 1
Mouse
Rat
Cow
gastrulation brain homeobox 1
Opossum
gastrulation brain homeobox 1
Protein Structure (4 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q14549-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 4 of 4
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Protein-Protein Interactions (24)
1 – 10 of 24
GBX2
Tbio
Family: TF
Novelty: 0.01248026
p_int: 0.999999996
p_wrong: 4e-9
Data Source: BioPlex
SOHLH1
Tbio
Family: TF
Novelty: 0.04218087
Score: 0.802
Data Source: STRINGDB
LHX8
Tbio
Family: TF
Novelty: 0.01815234
Score: 0.773
Data Source: STRINGDB
LHX6
Tbio
Family: TF
Novelty: 0.01603143
Score: 0.561
Data Source: STRINGDB
TCF7L1
Tbio
Family: TF
Novelty: 0.03807371
Score: 0.512
Data Source: STRINGDB
PBX3
Tbio
Family: TF
Novelty: 0.01516183
Score: 0.506
Data Source: STRINGDB
LRRC7
Tbio
Novelty: 0.03409889
Score: 0.495
Data Source: STRINGDB
ZFHX4
Tbio
Family: TF
Novelty: 0.06538087
Score: 0.495
Data Source: STRINGDB
PBX1
Tbio
Family: TF
Novelty: 0.00329442
Score: 0.481
Data Source: STRINGDB
LMO4
Tbio
Novelty: 0.08806373
Score: 0.47
Data Source: STRINGDB
Publication Statistics
PubMed Score  12.76

PubMed score by year
PubTator Score  2.73

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer