Tbio GBX1 Homeobox protein GBX-1

Protein Summary

Uniprot Accession IDs

• Q14549

Gene Name

• GBX1

Ensembl ID

• ENST00000297537
• ENSP00000297537
• ENSG00000164900

Symbol

• Huh-17

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.63
PubMedID	0.59
biological process	0.58
protein domain	0.58
transcription factor binding site profile	0.57

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Helix-turn-helix Transcription Factor / Homeodomain Transcription Factor / Homeobox Protein Gbx-1

Protein / Nucleic Acid Binding / Dna Binding Protein / Homeobox Protein Gbx-1

DTO Classes

Protein / Transcription Factor / Helix-turn-helix Transcription Factor / Homeodomain Transcription Factor / Homeobox Protein Gbx-1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.36   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 115   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.36   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0