HNF4G
Hepatocyte nuclear factor 4-gamma
Protein Classes
Protein Summary
Transcription factor. Has a lower transcription activation potential than HNF4-alpha.
- ENST00000354370
- ENSP00000346339
- ENSG00000164749
- ENST00000396423
- ENSP00000379701
- NR2A2
- NR2A2
- NR2A3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.88 | ||
protein domain | 0.85 | ||
microRNA | 0.8 | ||
molecular function | 0.76 | ||
biological process | 0.56 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 14.7 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 173 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 14.7 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 173 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 10
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id | Ligand | Method | Resolution (Å) | M.W. (kDa) | Pub Year | Title |
|---|
PDB Structure Id | M.W. | Resolution | Pub Year |
|---|
Pathways (8)
Reactome (7)
KEGG (1)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 5 of 7
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Developmental Biology | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Nuclear Receptor transcription pathway | ||||
Reactome | RNA Polymerase II Transcription | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Developmental Biology | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Nuclear Receptor transcription pathway | ||||
RNA Polymerase II Transcription | ||||
Gene Ontology Terms (11)
Functions (7)
Components (1)
Processes (3)
Items per page:
10
1 – 7 of 7
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred by Curator (IC) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Protein-Protein Interactions (53)
1 – 10 of 53
HNF1A
Family: TF
Novelty: 0.00145707
Score: 0.959
Data Source: STRINGDB
MED1
Family: Enzyme
Novelty: 0.01259825
Score: 0.901
Data Source: STRINGDB
PFKFB1
Family: Kinase
Novelty: 0.05463358
Score: 0.75
Data Source: STRINGDB
A1CF
Novelty: 0.01084046
Score: 0.715
Data Source: STRINGDB
B3GNT4
Family: Enzyme
Novelty: 0.56499261
Score: 0.674
Data Source: STRINGDB
FOXA2
Family: TF
Novelty: 0.00339972
Score: 0.64
Data Source: STRINGDB
FOXA1
Family: TF
Novelty: 0.00323694
Score: 0.621
Data Source: STRINGDB
UBE2Q2
Novelty: 0.13638143
Score: 0.617
Data Source: STRINGDB
PCK1
Family: Kinase
Novelty: 0.00439852
Score: 0.613
Data Source: STRINGDB
FADS3
Family: Enzyme
Novelty: 0.05947668
Score: 0.609
Data Source: STRINGDB
Publication Statistics
PubMed Score 14.70
PubMed score by year
PubTator Score 13.48
PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
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