NFE2L1
Endoplasmic reticulum membrane sensor NFE2L1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
kinase perturbation | 0.96 | ||
transcription factor binding site profile | 0.94 | ||
molecular function | 0.88 | ||
transcription factor | 0.85 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 4 | 4 | 80.1 | |||||
triglyceride measurement | 3 | 2 | 3 | 75.4 | |||||
hemoglobin measurement | 1 | 1 | 1 | 72.9 | |||||
BMI-adjusted hip circumference | 2 | 2 | 3 | 66.6 | |||||
hematocrit | 1 | 1 | 1 | 63.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 4 | 80.1 | |||||
triglyceride measurement | 3 | 75.4 | |||||
hemoglobin measurement | 1 | 72.9 | |||||
BMI-adjusted hip circumference | 3 | 66.6 | |||||
hematocrit | 1 | 63.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | nuclear factor, erythroid 2 like 1 | VGNC:9473 | 455185 | |||||
Macaque | nuclear factor, erythroid 2 like 1 | 695404 | ||||||
Mouse | MGI:99421 | 18023 | ||||||
Dog | nuclear factor, erythroid 2 like 1 | VGNC:43772 | 403692 | |||||
Cow | nuclear factor, erythroid 2 like 1 | VGNC:32035 | 534582 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | nuclear factor, erythroid 2 like 1 | |||||
Macaque | nuclear factor, erythroid 2 like 1 | |||||
Mouse | ||||||
Dog | nuclear factor, erythroid 2 like 1 | |||||
Cow | nuclear factor, erythroid 2 like 1 | |||||
PMID | Year | Title |
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