DYNC1H1
Cytoplasmic dynein 1 heavy chain 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.99 | ||
hub protein | 0.98 | ||
kinase perturbation | 0.98 | ||
molecular function | 0.98 | ||
transcription factor perturbation | 0.98 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | AURKA Activation by TPX2 | ||||
Reactome | Adaptive Immune System | ||||
Reactome | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Reactome | Amplification of signal from the kinetochores | ||||
Reactome | Anchoring of the basal body to the plasma membrane | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
AURKA Activation by TPX2 | ||||
Adaptive Immune System | ||||
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Amplification of signal from the kinetochores | ||||
Anchoring of the basal body to the plasma membrane | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | FlyBase | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 1 | 1 | 1 | 50.6 | |||||
creatinine measurement | 1 | 1 | 1 | 33.1 | |||||
blood protein measurement | 1 | 1 | 1 | 30.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
red blood cell distribution width | 1 | 50.6 | |||||
creatinine measurement | 1 | 33.1 | |||||
blood protein measurement | 1 | 30.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | dynein cytoplasmic 1 heavy chain 1 | VGNC:9048 | 453171 | |||||
Macaque | dynein cytoplasmic 1 heavy chain 1 | 718989 | ||||||
Mouse | MGI:103147 | 13424 | ||||||
Rat | RGD:2511 | 29489 | ||||||
Dog | dynein cytoplasmic 1 heavy chain 1 | VGNC:40143 | 480437 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | dynein cytoplasmic 1 heavy chain 1 | |||||
Macaque | dynein cytoplasmic 1 heavy chain 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | dynein cytoplasmic 1 heavy chain 1 | |||||
PMID | Year | Title |
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