WRN
Werner syndrome ATP-dependent helicase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 1 | ||
protein domain | 1 | ||
biological process | 0.78 | ||
cellular component | 0.74 | ||
disease perturbation | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle Checkpoints | ||||
Reactome | DNA Double-Strand Break Repair | ||||
Reactome | DNA Repair | ||||
Reactome | G2/M Checkpoints | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell Cycle | ||||
Cell Cycle Checkpoints | ||||
DNA Double-Strand Break Repair | ||||
DNA Repair | ||||
G2/M Checkpoints | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | MGI | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mathematical ability | 4 | 3 | 4 | 91.5 | |||||
self reported educational attainment | 2 | 3 | 3 | 89.8 | |||||
cognitive function measurement | 3 | 2 | 4 | 78.2 | |||||
4 | 4 | 3 | 1 | 75.7 | |||||
body mass index | 2 | 2 | 2 | 72.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mathematical ability | 4 | 91.5 | |||||
self reported educational attainment | 3 | 89.8 | |||||
cognitive function measurement | 4 | 78.2 | |||||
3 | 1 | 75.7 | |||||
body mass index | 2 | 72.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | Werner syndrome RecQ like helicase | VGNC:7604 | 472732 | |||||
Macaque | Werner syndrome RecQ like helicase | 695678 | ||||||
Mouse | MGI:109635 | 22427 | ||||||
Rat | RGD:1564788 | 290805 | ||||||
Dog | Werner syndrome RecQ like helicase | 493997 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | Werner syndrome RecQ like helicase | |||||
Macaque | Werner syndrome RecQ like helicase | |||||
Mouse | ||||||
Rat | ||||||
Dog | Werner syndrome RecQ like helicase | |||||
PMID | Year | Title |
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