SCRIB
Protein scribble homolog
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 0.99 | ||
transcription factor binding site profile | 0.84 | ||
ligand (protein) perturbation | 0.83 | ||
disease perturbation | 0.79 | ||
histone modification site profile | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Asymmetric localization of PCP proteins | ||||
Reactome | Beta-catenin independent WNT signaling | ||||
Reactome | PCP/CE pathway | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by WNT | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Asymmetric localization of PCP proteins | ||||
Beta-catenin independent WNT signaling | ||||
PCP/CE pathway | ||||
Signal Transduction | ||||
Signaling by WNT | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
diastolic blood pressure | 2 | 2 | 2 | 54.4 | |||||
age at menarche | 1 | 1 | 1 | 24.5 | |||||
appendicular lean mass | 1 | 1 | 1 | 21.5 | |||||
hip circumference | 1 | 1 | 1 | 6.3 | |||||
1 | 1 | 0 | 1.1 | 3.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
diastolic blood pressure | 2 | 54.4 | |||||
age at menarche | 1 | 24.5 | |||||
appendicular lean mass | 1 | 21.5 | |||||
hip circumference | 1 | 6.3 | |||||
0 | 1.1 | 3.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | scribbled planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:30377] | |||||||
Mouse | MGI:2145950 | 105782 | ||||||
Rat | RGD:1565055 | 362938 | ||||||
Dog | scribbled planar cell polarity protein | VGNC:45931 | 100685037 | |||||
Horse | scribbled planar cell polarity protein | VGNC:22750 | 100063454 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | scribbled planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:30377] | |||||
Mouse | ||||||
Rat | ||||||
Dog | scribbled planar cell polarity protein | |||||
Horse | scribbled planar cell polarity protein | |||||
PMID | Year | Title |
---|