You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
TOB2
Protein Tob2

Protein Summary
Description
Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases. TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM, Apr 2004]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000327492
  • ENSP00000331305
  • ENSG00000183864

Symbol
  • KIAA1663
  • TOB4
  • TROB2
  • TOB4
  • TOBL
  • APRO5
  • TROB2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.97
virus perturbation
0.95
kinase perturbation
0.93
transcription factor perturbation
0.88
disease perturbation
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.95   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 147   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.95   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 147   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0