Tbio COL9A3 Collagen alpha-3(IX) chain

Protein Summary

Description

Structural component of hyaline cartilage and vitreous of the eye. This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. Mutations in this gene are associated with multiple epiphyseal dysplasia type 3. [provided by RefSeq, Jan 2010]

Uniprot Accession IDs

• Q14050
• Q13681
• Q9H4G9
• Q9UPE2

Gene Name

• COL9A3

Ensembl ID

• ENST00000343916
• ENSP00000341640
• ENSG00000092758
• ENST00000649368
• ENSP00000496793

Symbol

• IDD
• MED
• EDM3
• DJ885L7.4.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.87
PubMedID	0.73
cell type or tissue	0.65
tissue sample	0.61
small molecule perturbation	0.6

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.86   (req: < 5)

Gene RIFs: 23   (req: <= 3)

Antibodies: 164   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.86   (req: >= 5)

Gene RIFs: 23   (req: > 3)

Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0