PRKG1
cGMP-dependent protein kinase 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
trait | 1 | ||
molecular function | 0.99 | ||
gene perturbation | 0.89 | ||
hub protein | 0.82 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Beta-catenin independent WNT signaling | ||||
Reactome | Ca2+ pathway | ||||
Reactome | Hemostasis | ||||
Reactome | Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Beta-catenin independent WNT signaling | ||||
Ca2+ pathway | ||||
Hemostasis | ||||
Immune System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Mutant Phenotype (IMP) | BHF-UCL | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body height | 2 | 2 | 2 | 49.2 | |||||
body mass index | 2 | 1 | 2 | 42.3 | |||||
2 | 2 | 0 | 1.1 | 37.3 | |||||
self reported educational attainment | 2 | 2 | 2 | 37.3 | |||||
dickkopfârelated protein 1 measurement | 1 | 1 | 1 | 32.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body height | 2 | 49.2 | |||||
body mass index | 2 | 42.3 | |||||
0 | 1.1 | 37.3 | |||||
self reported educational attainment | 2 | 37.3 | |||||
dickkopfârelated protein 1 measurement | 1 | 32.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | protein kinase, cGMP-dependent, type I | 744467 | ||||||
Macaque | protein kinase, cGMP-dependent, type I | 703356 | ||||||
Mouse | MGI:108174 | 19091 | ||||||
Dog | protein kinase cGMP-dependent 1 | VGNC:49948 | 609616 | |||||
Horse | protein kinase, cGMP-dependent, type I [Source:HGNC Symbol;Acc:HGNC:9414] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | protein kinase, cGMP-dependent, type I | |||||
Macaque | protein kinase, cGMP-dependent, type I | |||||
Mouse | ||||||
Dog | protein kinase cGMP-dependent 1 | |||||
Horse | protein kinase, cGMP-dependent, type I [Source:HGNC Symbol;Acc:HGNC:9414] | |||||
PMID | Year | Title |
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