Protein Summary
May be involved in intra-Golgi retrograde transport. The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]
- ENST00000292538
- ENSP00000292538
- ENSG00000257923
- ENST00000393824
- ENSP00000377410
- ENST00000437600
- ENSP00000414091
- ENST00000547394
- ENSP00000449371
- ENST00000622516
- ENSP00000484760
- CUTL1
- CDP
- CUX
- p75
- CASP
- CDP1
- COY1
- Clox
- GDDI
- p100
- p110
- p200
- CUTL1
- GOLIM6
- CDP/Cut
- Cux/CDP
- Nbla10317
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
biological process | 0 | ||
biological term | 0 | ||
cell line | 0 | ||
cell type or tissue | 0 | ||
cellular component | 0 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 378.1 (req: < 5)
Gene RIFs: 60 (req: <= 3)
Antibodies: 368 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 378.1 (req: >= 5)
Gene RIFs: 60 (req: > 3)
Antibodies: 368 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (160)
Nearest Tclin Targets
Pathways (11)
Reactome (10)
WikiPathways (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Disease | ||||
Reactome | Diseases of signal transduction | ||||
Reactome | FGFR1 mutant receptor activation | ||||
Reactome | Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Reactome | Intra-Golgi traffic | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Disease | ||||
Diseases of signal transduction | ||||
FGFR1 mutant receptor activation | ||||
Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Intra-Golgi traffic | ||||
Viral Interactions (0)
Gene Ontology Terms (6)
Functions (1)
Components (4)
Processes (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Disease Associations ()
GWAS Traits (24)
Items per page:
1 – 5 of 24
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 3 | 3 | 10 | 97.4 | |||||
platelet crit | 2 | 2 | 6 | 92.5 | |||||
sex hormone-binding globulin measurement | 6 | 2 | 12 | 83 | |||||
eosinophil count | 2 | 3 | 6 | 79.3 | |||||
chronotype measurement | 2 | 2 | 4 | 1 | 74 | ||||
Items per page:
1 – 5 of 24
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
mean platelet volume | 10 | 97.4 | |||||
platelet crit | 6 | 92.5 | |||||
sex hormone-binding globulin measurement | 12 | 83 | |||||
eosinophil count | 6 | 79.3 | |||||
chronotype measurement | 4 | 1 | 74 | ||||
Find similar targets by:
IDG Resources
Orthologs (8)
1 – 5 of 8
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | cut like homeobox 1 | VGNC:13642 | 450166 | |||||
Macaque | cut-like homeobox 1 | 574390 | ||||||
Rat | RGD:620618 | 116639 | ||||||
Dog | cut like homeobox 1 | VGNC:39738 | 489821 | |||||
Opossum | cut like homeobox 1 | 100028646 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | cut like homeobox 1 | |||||
Macaque | cut-like homeobox 1 | |||||
Rat | ||||||
Dog | cut like homeobox 1 | |||||
Opossum | cut like homeobox 1 | |||||
Publication Statistics
PubMed Score 378.10
PubMed score by year
PubTator Score 1088.23
PubTator score by year
Related Publications
Text Mined References (91)
GeneRif Annotations (60)
Items per page:
0 of 0
PMID | Year | Title |
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