Tbio Q13948 Protein CASP

Protein Summary

Description

May be involved in intra-Golgi retrograde transport. The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]

Uniprot Accession IDs

• Q13948
• B3KWH3
• B3KWH8
• B4DZZ2
• G3V1Z6
• J3KPQ6
• Q53GU9
• Q8TBS3

Gene Name

• CUX1

Ensembl ID

• ENST00000292538
• ENSP00000292538
• ENSG00000257923
• ENST00000393824
• ENSP00000377410
• ENST00000437600
• ENSP00000414091
• ENST00000547394
• ENSP00000449371
• ENST00000622516
• ENSP00000484760

Symbol

• CUTL1
• CDP
• CUX
• p75
• CASP
• CDP1
• COY1
• Clox
• GDDI
• p100
• p110
• p200
• CUTL1
• GOLIM6
• CDP/Cut
• Cux/CDP
• Nbla10317

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 577.48   (req: < 5)

Gene RIFs: 72   (req: <= 3)

Antibodies: 368   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 577.48   (req: >= 5)

Gene RIFs: 72   (req: > 3)

Antibodies: 368   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0