SLC12A1
Solute carrier family 12 member 1
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.73 | ||
cell type or tissue | 0.67 | ||
drug | 0.65 | ||
biological term | 0.6 | ||
molecular function | 0.6 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cation-coupled Chloride cotransporters | ||||
Reactome | Defective SLC12A1 causes Bartter syndrome 1 (BS1) | ||||
Reactome | Disease | ||||
Reactome | Disorders of transmembrane transporters | ||||
Reactome | SLC transporter disorders | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cation-coupled Chloride cotransporters | ||||
Defective SLC12A1 causes Bartter syndrome 1 (BS1) | ||||
Disease | ||||
Disorders of transmembrane transporters | ||||
SLC transporter disorders | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
skin pigmentation measurement | 3 | 3 | 2 | 3.5 | 92.1 | ||||
skin pigmentation | 2 | 2 | 0 | 8.2 | 84.6 | ||||
lymphocyte count | 2 | 2 | 2 | 71.4 | |||||
lymphocyte percentage of leukocytes | 1 | 1 | 1 | 51.7 | |||||
body height | 1 | 1 | 1 | 27.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
skin pigmentation measurement | 2 | 3.5 | 92.1 | ||||
skin pigmentation | 0 | 8.2 | 84.6 | ||||
lymphocyte count | 2 | 71.4 | |||||
lymphocyte percentage of leukocytes | 1 | 51.7 | |||||
body height | 1 | 27.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 12 member 1 | VGNC:7779 | 453410 | |||||
Macaque | solute carrier family 12 member 1 | 714289 | ||||||
Mouse | MGI:103150 | 20495 | ||||||
Rat | RGD:3685 | 25065 | ||||||
Dog | solute carrier family 12 member 1 | VGNC:46218 | 478292 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | solute carrier family 12 member 1 | |||||
Macaque | solute carrier family 12 member 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 12 member 1 | |||||
PMID | Year | Title |
---|