GPR17
Uracil nucleotide/cysteinyl leukotriene receptor
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
ligand (chemical) | 0.56 | ||
cell type or tissue | 0.52 | ||
pathway | 0.52 | ||
tissue sample | 0.51 | ||
gene perturbation | 0.49 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
Reactome | Eicosanoid ligand-binding receptors | ||||
Reactome | G alpha (i) signalling events | ||||
Reactome | G alpha (q) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Class A/1 (Rhodopsin-like receptors) | ||||
Eicosanoid ligand-binding receptors | ||||
G alpha (i) signalling events | ||||
G alpha (q) signalling events | ||||
GPCR downstream signalling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
myeloid white cell count | 1 | 1 | 1 | 57.8 | |||||
lymphocyte count | 1 | 1 | 1 | 46.5 | |||||
protein C measurement | 1 | 1 | 1 | 30.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
myeloid white cell count | 1 | 57.8 | |||||
lymphocyte count | 1 | 46.5 | |||||
protein C measurement | 1 | 30.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | G protein-coupled receptor 17 | VGNC:10830 | 100611956 | |||||
Macaque | G protein-coupled receptor 17 | 699576 | ||||||
Mouse | MGI:3584514 | 574402 | ||||||
Rat | RGD:1589785 | 767613 | ||||||
Dog | G protein-coupled receptor 17 | VGNC:41414 | 100688664 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | G protein-coupled receptor 17 | |||||
Macaque | G protein-coupled receptor 17 | |||||
Mouse | ||||||
Rat | ||||||
Dog | G protein-coupled receptor 17 | |||||
PMID | Year | Title |
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