TRIM28
Transcription intermediary factor 1-beta
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug perturbation | 1 | ||
hub protein | 1 | ||
interacting protein | 1 | ||
co-expressed gene | 0.99 | ||
protein domain | 0.99 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | RNA Polymerase II Transcription | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Metabolism of proteins | ||||
Post-translational protein modification | ||||
RNA Polymerase II Transcription | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 3 | 2 | 3 | 78.7 | |||||
mathematical ability | 3 | 2 | 3 | 64 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 49.5 | |||||
red blood cell distribution width | 1 | 1 | 1 | 49.5 | |||||
mean platelet volume | 1 | 1 | 1 | 44.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 3 | 78.7 | |||||
mathematical ability | 3 | 64 | |||||
mean reticulocyte volume | 1 | 49.5 | |||||
red blood cell distribution width | 1 | 49.5 | |||||
mean platelet volume | 1 | 44.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | tripartite motif containing 28 | 711982 | ||||||
Mouse | MGI:109274 | 21849 | ||||||
Rat | RGD:620289 | 116698 | ||||||
Dog | tripartite motif containing 28 | VGNC:47811 | 403689 | |||||
Horse | tripartite motif containing 28 | VGNC:24499 | 100064831 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | tripartite motif containing 28 | |||||
Mouse | ||||||
Rat | ||||||
Dog | tripartite motif containing 28 | |||||
Horse | tripartite motif containing 28 | |||||
PMID | Year | Title |
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