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Tbio
PDZK1IP1
PDZK1-interacting protein 1

Protein Summary
Description
May play an important role in tumor biology.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294338
  • ENSP00000294338
  • ENSG00000162366
  • ENST00000371885
  • ENSP00000360952

Symbol
  • MAP17
  • DD96
  • SPAP
  • MAP17
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.88
gene perturbation
0.83
PubMedID
0.71
disease perturbation
0.68
small molecule perturbation
0.57


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 79.82   (req: < 5)
Gene RIFs: 17   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 79.82   (req: >= 5)
Gene RIFs: 17   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
2
2
2
71.6
mean reticulocyte volume
1
1
1
11.1
mean corpuscular volume
1
1
1
10.6
body height
1
1
1
5.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
2
71.6
mean reticulocyte volume
1
11.1
mean corpuscular volume
1
10.6
body height
1
5.3
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
PDZK1 interacting protein 1
VGNC:1442
743132
Mouse
MGI:1914432
67182
Rat
RGD:620952
81916
Dog
PDZK1 interacting protein 1
VGNC:44404
475365
Horse
PDZK1 interacting protein 1
VGNC:21293
100051481
Species
Name
OMA
EggNOG
Inparanoid
Chimp
PDZK1 interacting protein 1
Mouse
Rat
Dog
PDZK1 interacting protein 1
Horse
PDZK1 interacting protein 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q13113-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (32)
1 – 10 of 32
PDZK1
Tbio
Novelty: 0.01129974
Score: 0.764
Data Source: STRINGDB
ASPA
Tbio
Family: Enzyme
Novelty: 0.02701619
Score: 0.694
Data Source: STRINGDB
MAP10
Tbio
Novelty: 0.10409728
Score: 0.664
Data Source: STRINGDB
DMBT1
Tbio
Novelty: 0.00357297
Score: 0.661
Data Source: STRINGDB
MAP9
Tbio
Novelty: 0.08883282
Score: 0.657
Data Source: STRINGDB
LCN2
Tbio
Family: Enzyme
Novelty: 0.00034678
Score: 0.648
Data Source: STRINGDB
DNAJC7
Tbio
Novelty: 0.02133191
Score: 0.633
Data Source: STRINGDB
STIL
Tbio
Novelty: 0.01053211
Score: 0.612
Data Source: STRINGDB
MAP7
Tbio
Novelty: 0.01976296
Score: 0.593
Data Source: STRINGDB
IER5
Tbio
Novelty: 0.06965213
Score: 0.579
Data Source: STRINGDB
Publication Statistics
PubMed Score  79.82

PubMed score by year
PubTator Score  115.91

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer