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Tbio
ZNF154
Zinc finger protein 154

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a protein that belongs to the zinc finger Kruppel family of transcriptional regulators, whose members are thought to function in normal and abnormal cell growth and differentiation. Hypermethylation of this gene is associated with the recurrence of non muscle invasive bladder cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000451275
  • ENSP00000469633
  • ENSG00000179909
  • ENST00000512439
  • ENSP00000421258

Symbol
  • KIAA2003
  • pHZ-92
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.58
tissue sample
0.54
cell type or tissue
0.52
cell line
0.5
co-expressed gene
0.48


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.85   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.85   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Dog
zinc finger protein 154-like
100685225
Species
Name
OMA
EggNOG
Inparanoid
Dog
zinc finger protein 154-like
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q13106-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (20)
1 – 10 of 20
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.903
Data Source: STRINGDB
HTN3
Tbio
Novelty: 0.00825966
Score: 0.652
Data Source: STRINGDB
PCDHAC1
Tdark
Novelty: 0.3734734
Score: 0.587
Data Source: STRINGDB
FAM78A
Tdark
Novelty: 0.92171591
Score: 0.571
Data Source: STRINGDB
RIMS4
Tbio
Novelty: 0.12325795
Score: 0.565
Data Source: STRINGDB
CDKL2
Tchem
Family: Kinase
Novelty: 0.0669719
Score: 0.536
Data Source: STRINGDB
POU4F2
Tbio
Family: TF
Novelty: 0.00896203
Score: 0.511
Data Source: STRINGDB
ALKAL1
Tbio
Novelty: 0.12828794
Score: 0.511
Data Source: STRINGDB
STEAP4
Tbio
Family: Enzyme
Novelty: 0.01926607
Score: 0.491
Data Source: STRINGDB
PRAC1
Tbio
Novelty: 0.03902014
Score: 0.473
Data Source: STRINGDB
Publication Statistics
PubMed Score  8.85

PubMed score by year
PubTator Score  4.59

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer