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Tbio
ZNF154
Zinc finger protein 154

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a protein that belongs to the zinc finger Kruppel family of transcriptional regulators, whose members are thought to function in normal and abnormal cell growth and differentiation. Hypermethylation of this gene is associated with the recurrence of non muscle invasive bladder cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000451275
  • ENSP00000469633
  • ENSG00000179909
  • ENST00000512439
  • ENSP00000421258

Symbol
  • KIAA2003
  • pHZ-92
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.58
tissue sample
0.54
cell type or tissue
0.52
cell line
0.5
co-expressed gene
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.18   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.18   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (20)
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.903
Data Source:  STRINGDB
HTN3
Tbio
Novelty:  0.00825966
Score:  0.652
Data Source:  STRINGDB
PCDHAC1
Tdark
Novelty:  0.3734734
Score:  0.587
Data Source:  STRINGDB
FAM78A
Tdark
Novelty:  0.92171591
Score:  0.571
Data Source:  STRINGDB
RIMS4
Tbio
Novelty:  0.12325795
Score:  0.565
Data Source:  STRINGDB
CDKL2
Tchem
Family:  Kinase
Novelty:  0.0669719
Score:  0.536
Data Source:  STRINGDB
POU4F2
Tbio
Family:  TF
Novelty:  0.00896203
Score:  0.511
Data Source:  STRINGDB
ALKAL1
Tbio
Novelty:  0.12828794
Score:  0.511
Data Source:  STRINGDB
STEAP4
Tbio
Family:  Enzyme
Novelty:  0.01926607
Score:  0.491
Data Source:  STRINGDB
PRAC1
Tbio
Novelty:  0.03902014
Score:  0.473
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

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1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (7)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Sequence Alignment (ISA)
NTNU_SB
Non-traceable Author Statement (NAS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
3
4
90.6
mean reticulocyte volume
1
1
1
62.1
1
1
0
1.6
0.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
90.6
mean reticulocyte volume
1
62.1
0
1.6
0.4
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Dog
zinc finger protein 154-like
100685225
Species
Name
OMA
EggNOG
Inparanoid
Dog
zinc finger protein 154-like
Publication Statistics
PubMed Score 9.18
PubMed score by year
PubTator Score 4.59
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title