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Tbio
STRN3
Striatin-3

Protein Summary
Description
Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355683
  • ENSP00000347909
  • ENSG00000196792
  • ENST00000357479
  • ENSP00000350071

Symbol
  • GS2NA
  • SG2NA
  • SG2NA
  • S/G2NA
  • PPP2R6B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
0.96
kinase perturbation
0.88
protein domain
0.85
histone modification site profile
0.74
hub protein
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.6   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.6   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (20)
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (84)
1 – 10 of 84
CTTNBP2NL
Tbio
Novelty: 0.86196127
p_int: 0.999999917
p_ni: 8.3e-8
Score: 0.942
Data Source: BioPlex,STRINGDB
CTTNBP2
Tbio
Novelty: 0.00377498
p_int: 0.999999806
p_ni: 1.94e-7
Score: 0.906
Data Source: BioPlex,STRINGDB
MOB4
Tbio
Novelty: 0.04140583
p_int: 0.999999699
p_ni: 3.01e-7
Score: 0.96
Data Source: BioPlex,STRINGDB
SLMAP
Tbio
Novelty: 0.04279507
p_int: 0.999998986
p_ni: 0.000001014
Score: 0.958
Data Source: BioPlex,STRINGDB
TRAF3IP3
Tbio
Novelty: 0.22909091
p_int: 0.999998805
p_ni: 0.000001195
Score: 0.87
Data Source: BioPlex,STRINGDB
STRN
Tbio
Novelty: 0.01561194
p_int: 0.999998505
p_ni: 0.000001495
Score: 0.865
Data Source: BioPlex,STRINGDB
STRN4
Tbio
Novelty: 0.14202711
p_int: 0.999998256
p_ni: 0.000001744
Score: 0.871
Data Source: BioPlex,STRINGDB
SIKE1
Tbio
Novelty: 0.1439212
p_int: 0.999997603
p_ni: 0.000002396
p_wrong: 2e-9
Score: 0.918
Data Source: BioPlex,STRINGDB
STRIP1
Tbio
Novelty: 0.15362107
p_int: 0.999997257
p_ni: 0.000002743
Score: 0.963
Data Source: BioPlex,STRINGDB
STRIP2
Tbio
Novelty: 0.15494343
p_int: 0.999983505
p_ni: 0.00001646
p_wrong: 3.5e-8
Score: 0.965
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  6.60

PubMed score by year
PubTator Score  3.59

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer