Tbio STRN3 Striatin-3

Protein Summary

Description

Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.

Uniprot Accession IDs

• Q13033
• A2RTX7
• A6NHZ7
• Q9NRA5

Gene Name

• STRN3

Ensembl ID

• ENST00000355683
• ENSP00000347909
• ENSG00000196792
• ENST00000357479
• ENSP00000350071

Symbol

• GS2NA
• SG2NA
• SG2NA
• S/G2NA
• PPP2R6B

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
drug perturbation	0.96
kinase perturbation	0.88
protein domain	0.85
histone modification site profile	0.74
hub protein	0.71

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.21   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 119   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.21   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0