IFRD2
Interferon-related developmental regulator 2
Protein Summary
- ENST00000417626
- ENSP00000402849
- ENSG00000214706
- SM15
- IFNRP
- SKMc15
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.97 | ||
disease perturbation | 0.96 | ||
transcription factor binding site profile | 0.88 | ||
transcription factor perturbation | 0.8 | ||
small molecule perturbation | 0.65 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 31.69 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 145 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 31.69 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 145 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (30)
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (1)
Components (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Disease Associations ()
GWAS Traits (21)
Items per page:
1 – 5 of 21
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 7 | 14 | 99.5 | |||||
reticulocyte count | 2 | 4 | 8 | 98.7 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 85.1 | |||||
chronotype measurement | 1 | 2 | 0 | 1 | 78.7 | ||||
macrophage inflammatory protein 1b measurement | 1 | 2 | 2 | 66.2 | |||||
Items per page:
1 – 5 of 21
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
reticulocyte measurement | 14 | 99.5 | |||||
reticulocyte count | 8 | 98.7 | |||||
mean reticulocyte volume | 1 | 85.1 | |||||
chronotype measurement | 0 | 1 | 78.7 | ||||
macrophage inflammatory protein 1b measurement | 2 | 66.2 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Macaque | interferon related developmental regulator 2 | 702959 | ||||||
Mouse | MGI:1316708 | 15983 | ||||||
Rat | RGD:1310222 | 300994 | ||||||
Horse | interferon related developmental regulator 2 | VGNC:18957 | 100061975 | |||||
Cow | interferon related developmental regulator 2 | VGNC:30063 | 767939 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Macaque | interferon related developmental regulator 2 | |||||
Mouse | ||||||
Rat | ||||||
Horse | interferon related developmental regulator 2 | |||||
Cow | interferon related developmental regulator 2 | |||||
Publication Statistics
PubMed Score 31.69
PubMed score by year
PubTator Score 4.86
PubTator score by year
Related Publications
Text Mined References (10)
GeneRif Annotations (5)
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0 of 0
PMID | Year | Title |
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