You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
IFRD2
Interferon-related developmental regulator 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000417626
  • ENSP00000402849
  • ENSG00000214706

Symbol
  • SM15
  • IFNRP
  • SKMc15
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
disease perturbation
0.96
transcription factor binding site profile
0.88
transcription factor perturbation
0.8
small molecule perturbation
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.69   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 145   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.69   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 145   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
UBE2O
Tbio
Novelty:  0.07084123
p_int:  0.962405785
p_ni:  0.037594214
Score:  0.188
Data Source:  BioPlex,STRINGDB
EIF3J
Tbio
Novelty:  0.04648652
p_int:  0.93789105
p_ni:  0.06210895
Score:  0.271
Data Source:  BioPlex,STRINGDB
TRMT61A
Tbio
Family:  Enzyme
Novelty:  0.04443394
Score:  0.821
Data Source:  STRINGDB
COQ7
Tbio
Family:  Enzyme
Novelty:  0.01010794
Score:  0.634
Data Source:  STRINGDB
HSPBP1
Tbio
Novelty:  0.01176285
Score:  0.613
Data Source:  STRINGDB
NOP58
Tbio
Novelty:  0.02148045
Score:  0.567
Data Source:  STRINGDB
MRPS2
Tbio
Novelty:  0.14756204
Score:  0.555
Data Source:  STRINGDB
HYAL1
Tbio
Family:  Enzyme
Novelty:  0.00756819
Score:  0.532
Data Source:  STRINGDB
HYAL2
Tbio
Family:  Enzyme
Novelty:  0.00740331
Score:  0.497
Data Source:  STRINGDB
SIN3B
Tbio
Novelty:  0.04097105
Score:  0.495
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (21)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
3
7
14
99.5
reticulocyte count
2
4
8
98.7
mean reticulocyte volume
1
1
1
85.1
chronotype measurement
1
2
0
1
78.7
macrophage inflammatory protein 1b measurement
1
2
2
66.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
14
99.5
reticulocyte count
8
98.7
mean reticulocyte volume
1
85.1
chronotype measurement
0
1
78.7
macrophage inflammatory protein 1b measurement
2
66.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
interferon related developmental regulator 2
702959
Mouse
MGI:1316708
15983
Rat
RGD:1310222
300994
Horse
interferon related developmental regulator 2
VGNC:18957
100061975
Cow
interferon related developmental regulator 2
VGNC:30063
767939
Species
Name
OMA
EggNOG
Inparanoid
Macaque
interferon related developmental regulator 2
Mouse
Rat
Horse
interferon related developmental regulator 2
Cow
interferon related developmental regulator 2
Publication Statistics
PubMed Score 31.69
PubMed score by year
PubTator Score 4.86
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title