Tbio PNRC1 Proline-rich nuclear receptor coactivator 1

Protein Summary

Description

Nuclear receptor coactivator. May play a role in signal transduction.

Uniprot Accession IDs

• Q12796
• B2R6Q0
• E1P515
• Q5T7J6
• Q7Z5N0

Gene Name

• PNRC1

Ensembl ID

• ENST00000336032
• ENSP00000336931
• ENSG00000146278

Symbol

• PROL2
• B4-2
• PRR2
• PROL2
• PNAS-145

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.9
gene perturbation	0.81
small molecule perturbation	0.8
transcription factor	0.75
microRNA	0.7

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 173   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 38   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 173   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 38   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0