Tbio NUP160 Nuclear pore complex protein Nup160

Protein Summary

Description

Involved in poly(A)+ RNA transport. NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004]

Uniprot Accession IDs

• Q12769
• B4DYE8
• B4E2J9
• Q08AD3
• Q7Z5X6
• Q96GB3
• Q9H660

Gene Name

• NUP160

Ensembl ID

• ENST00000378460
• ENSP00000367721
• ENSG00000030066
• ENST00000526870
• ENSP00000431495
• ENST00000643285
• ENSP00000495820
• ENSG00000285358
• ENST00000645800
• ENSP00000496541

Symbol

• KIAA0197
• NUP120
• NPHS19

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
pathway	1
virus perturbation	0.88
kinase perturbation	0.84
transcription factor binding site profile	0.84
histone modification site profile	0.74

Protein Classes

PANTHER Classes

Protein / Transporter / Nuclear Pore Complex Protein Nup160

DTO Classes

Protein / Transporter / Nuclear Pore Complex Protein Nup160

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.89   (req: < 5)

Gene RIFs: 12   (req: <= 3)

Antibodies: 213   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.89   (req: >= 5)

Gene RIFs: 12   (req: > 3)

Antibodies: 213   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0