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Tbio
FUT5
Alpha-(1,3)-fucosyltransferase 5

Protein Summary
Description
May catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000252675
  • ENSP00000252675
  • ENSG00000130383

Symbol
  • FUC-TV
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.7
tissue sample
0.56
gene perturbation
0.53
cellular component
0.49
microRNA
0.47


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.08   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.08   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (51)
FUT2
Tbio
Family:  Enzyme
Novelty:  0.0009286
Score:  0.976
Data Source:  STRINGDB
FUT1
Tbio
Family:  Enzyme
Novelty:  0.00597206
Score:  0.975
Data Source:  STRINGDB
B4GALT1
Tbio
Family:  Enzyme
Novelty:  0.0073693
Score:  0.956
Data Source:  STRINGDB
ST3GAL6
Tbio
Family:  Enzyme
Novelty:  0.05226811
Score:  0.946
Data Source:  STRINGDB
ST8SIA1
Tbio
Family:  Enzyme
Novelty:  0.02322808
Score:  0.937
Data Source:  STRINGDB
B4GALT4
Tbio
Family:  Enzyme
Novelty:  0.11226614
Score:  0.935
Data Source:  STRINGDB
B4GALT3
Tbio
Family:  Enzyme
Novelty:  0.04015046
Score:  0.931
Data Source:  STRINGDB
B3GNT3
Tbio
Family:  Enzyme
Novelty:  0.04325325
Score:  0.931
Data Source:  STRINGDB
B4GALT2
Tbio
Family:  Enzyme
Novelty:  0.03492512
Score:  0.928
Data Source:  STRINGDB
B3GNT4
Tbio
Family:  Enzyme
Novelty:  0.47935258
Score:  0.92
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Blood group systems biosynthesis (R-HSA-9033658)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Blood group systems biosynthesis
Reactome
Lewis blood group biosynthesis
Reactome
Metabolism
Reactome
Metabolism of carbohydrates
Name
Explore in Pharos
Explore in Source
Blood group systems biosynthesis
Lewis blood group biosynthesis
Metabolism
Metabolism of carbohydrates
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (23)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heart rate variability measurement
4
4
8
97.1
cancer biomarker measurement
1
3
4
97
cancer antigen 19.9 measurement
1
2
2
91
vitamin B12 measurement
2
3
2
49.8
88.8
N-glycan measurement
2
1
18
79.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heart rate variability measurement
8
97.1
cancer biomarker measurement
4
97
cancer antigen 19.9 measurement
2
91
vitamin B12 measurement
2
49.8
88.8
N-glycan measurement
18
79.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
fucosyltransferase 5
VGNC:6626
455628
Species
Name
OMA
EggNOG
Inparanoid
Chimp
fucosyltransferase 5
Publication Statistics
PubMed Score 35.08
PubMed score by year
PubTator Score 35.22
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title