You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TMEM62
Transmembrane protein 62

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000260403
  • ENSP00000260403
  • ENSG00000137842
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.96
cell type or tissue
0.7
cell line
0.65
tissue sample
0.64
small molecule perturbation
0.63


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.77   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.77   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
1
1
59.6
high density lipoprotein cholesterol measurement
1
1
1
53.3
apolipoprotein A 1 measurement
1
1
1
45.2
self reported educational attainment
1
1
1
26.6
household income
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
59.6
high density lipoprotein cholesterol measurement
1
53.3
apolipoprotein A 1 measurement
1
45.2
self reported educational attainment
1
26.6
household income
1
21.5
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 62
VGNC:1590
453372
Macaque
transmembrane protein 62
709505
Mouse
MGI:2139461
96957
Rat
RGD:1305647
311350
Dog
transmembrane protein 62
VGNC:47594
478271
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 62
Macaque
transmembrane protein 62
Mouse
Rat
Dog
transmembrane protein 62
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q0P6H9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (14)
1 – 10 of 14
KLRC4
Tbio
Novelty:  0.16922525
p_int:  0.999993878
p_ni:  0.000006099
p_wrong:  2.3e-8
Data Source:  BioPlex
UPK1A
Tbio
Novelty:  0.01748122
p_int:  0.999979759
p_ni:  0.000019809
p_wrong:  4.32e-7
Score:  0.188
Data Source:  BioPlex,STRINGDB
SCGB2A1
Tbio
Novelty:  0.01902973
p_int:  0.92320508
p_ni:  0.016905423
p_wrong:  0.059889497
Data Source:  BioPlex
ZFP37
Tbio
Family:  TF
Novelty:  0.12072115
Score:  0.627
Data Source:  STRINGDB
PPP2R3C
Tbio
Family:  Enzyme
Novelty:  0.02970644
Score:  0.601
Data Source:  STRINGDB
RHBDF2
Tbio
Family:  Enzyme
Novelty:  0.02487334
Score:  0.596
Data Source:  STRINGDB
SH3BGRL3
Tbio
Novelty:  0.08079434
Score:  0.577
Data Source:  STRINGDB
COA3
Tbio
Family:  Enzyme
Novelty:  0.04949473
Score:  0.575
Data Source:  STRINGDB
PLA2G15
Tbio
Family:  Enzyme
Novelty:  0.01546393
Score:  0.559
Data Source:  STRINGDB
NPLOC4
Tbio
Novelty:  0.01690434
Score:  0.534
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.77

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer