Tdark ZNF415 Zinc finger protein 415

Protein Summary

Description

Involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP-1 and p53/TP53.

Uniprot Accession IDs

• Q09FC8
• F5H287
• Q09FC7
• Q09FC9
• Q09FD0
• Q6NSZ2
• Q6P3S0
• Q9NUR2

Gene Name

• ZNF415

Ensembl ID

• ENST00000243643
• ENSP00000243643
• ENSG00000170954
• ENST00000421033
• ENSP00000395055
• ENST00000500065
• ENSP00000439435
• ENST00000601493
• ENSP00000472911

Symbol

• Pact
• ZfLp

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.72
cell type or tissue	0.67
cellular component	0.67
phenotype	0.55
tissue	0.51

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.98   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 132   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.98   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 132   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0