Tbio SIGLEC14 Sialic acid-binding Ig-like lectin 14

Protein Summary

Description

Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors.

Uniprot Accession IDs

• Q08ET2
• Q6UXG0
• Siglec-14

Gene Name

• SIGLEC14

Ensembl ID

• ENST00000360844
• ENSP00000354090
• ENSG00000254415

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
microRNA	0.79
tissue sample	0.71
tissue	0.67
cell line	0.49

Protein Classes

PANTHER Classes

Protein / Structural Protein / Myelin Protein / Sialic Acid-binding Ig-like Lectin 14

Protein / Signaling Molecule / Membrane-bound Signaling Molecule / Sialic Acid-binding Ig-like Lectin 14

Protein / Receptor / Cytokine Receptor / Immunoglobulin Receptor Superfamily / Sialic Acid-binding Ig-like Lectin 14

Protein / Defense/immunity Protein / Immunoglobulin Receptor Superfamily / Sialic Acid-binding Ig-like Lectin 14

Protein / Cell Adhesion Molecule / Immunoglobulin Superfamily Cell Adhesion Molecule / Sialic Acid-binding Ig-like Lectin 14

DTO Classes

Protein / Receptor / Cytokine Receptor / Immunoglobulin Receptor Superfamily / Sialic Acid-binding Ig-like Lectin 14

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.48   (req: < 5)

Gene RIFs: 12   (req: <= 3)

Antibodies: 116   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.48   (req: >= 5)

Gene RIFs: 12   (req: > 3)

Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0